Analysis of the Relationship Between Surgical Treatment and Postoperative Tumor Recurrence and Postoperative Quality of Life in Patients with Primary Liver Cancer
DONG De-cheng, SUN Ming-hui, ZHANG Pei-ming
the Commercial Employees Hospital of Qingdao, Shandong 266000, China
Abstract：【Objective】To analyze the relationship between surgical treatment and postoperative tumor recurrence and postoperative quality of life in patients with primary liver cancer (PLC). 【Methods】A total of 358 patients with PLC were divided into the liver resection group (n=308) and the liver transplantation group (n=50). According to different liver function, the patients were further divided into the moderate to severe cirrhosis group (n=34), mild cirrhosis group (n=230) and non-cirrhosis group (n=44). The postoperative survival rate, tumor recurrence rate and quality of life were compared between the two groups. 【Results】There were no significant differences in 1, 3 and 5-year cumulative survival rates and cumulative recurrence rate between the liver resection group and the liver transplantation group (P>0.05). The 3-year and 5-year survival rates of patients with moderate to severe liver cirrhosis were lower and the 1-year, 3-year and 5-year cumulative recurrence rates were higher than in the mild cirrhosis patients and the patients without cirrhosis (P<0.01). However, there was no significant difference between the mild cirrhosis group and the non-cirrhosis (P>0.05). The scores of physical function (PH), mental function (PS), symptoms/side effects (ST), social function (SO), self-evaluation and the total score were lower in the liver resection group than the liver transplantation group (P<0.01). Correlation analysis showed that the two operation methods and the degree of liver cirrhosis were closely related to tumor recurrence rate and quality of life. 【Conclusion】 The short-term and long-term curative effects of liver resection and liver transplantation are similar in the treatment of non-cirrhosis or mild cirrhosis. However, the tumor recurrence rate is high in patients with moderate to severe liver cirrhosis after liver resection, which will decrease the quality of life.
董德成,孙明辉,张培铭. 原发性肝癌的治疗方法与术后肿瘤复发和生活质量的关系[J]. 医学临床研究, 2017, 34(6): 1084-1086.
DONG De-cheng, SUN Ming-hui, ZHANG Pei-ming. Analysis of the Relationship Between Surgical Treatment and Postoperative Tumor Recurrence and Postoperative Quality of Life in Patients with Primary Liver Cancer. JOURNAL OF CLINICAL RESEARCH, 2017, 34(6): 1084-1086.
2017, Vol. 34 
