Abstract： Objective To compared the effects of fentanyl and oxycodone respectively combined with propofol in hysteroscopic surgery. Methods Eighty-eight patients who underwent elective hysteroscopic surgery were randomly divided into the control group and the observation group with 44 cases in each group. The control group was treated with fentanyl combined with propofol anesthesia, while the observation group was treated with oxycodone combined with propofol. The changes of heart rate (HR), mean arterial pressure (MAP) and blood oxygen saturation (SpO2), condition of surgery, postoperative sedation scores and incidence of adverse reactions were compared between groups. Results ①HR, MAP and SpO2 at the end of injection (T1), uterine dilation (T2), 5min after the beginning of surgery (T3) and withdrawal of vagina dilator (T4) were lower than those before anesthesia (T0), and after recovery (T5), MAP were lower than those at T0 (P<0.05). At T2, T3 and T4, SpO2 of observation group were higher than those of the control group (P<0.05). ②There were no significant differences in the surgical time, recovery time and Ramsay sedation score between the two groups (P>0.05). The dosage of propofol in the observation group was lower than that in the control group during surgery (P<0.05). ③The incidence of adverse reactions in the observation group was slightly lower than that in the control group, but the difference was not significant (P>0.05). Conclusion The sedative effects of both oxycodone and fentanyl combined with propofol are good in hysteroscopic surgery, but oxycodone combined with propofol has little effect on the respiratory inhibition in patients with less dosage of propofol and higher safety.
李赟赟. 芬太尼与羟考酮分别复合丙泊酚在宫腔镜手术中的麻醉效果比较[J]. 医学临床研究, 2017, 34(5): 903-905.
LI Yun-yun. Comparison of Fentanyl and Oxycodone Respectively Combined with Propofol in Hysteroscopic Surgery. JOURNAL OF CLINICAL RESEARCH, 2017, 34(5): 903-905.
2017, Vol. 34 
