Abstract: Objective To investigate the clinical value of noninvasive intracranial pressure monitoring in the treatment of posttraumatic acute diffuse brain swelling (PADBS) and to evaluate its significance to the prognosis. Methods A retrospective analysis of the clinical data of 69 patients with PADBS treated by neurosurgery from January 2009 to December 2014 in the 163 Hospital of People's Liberation Army was performed. All patients were in ICU ward within 2~24 hours after injury and were monitored by noninvasive intracranial pressure monitor (MICP-1A, flash visual evoked potential noninvasive intracranial pressure detection analyzer). Patients were divided into mild, moderate, and severe intracranial hypertension according to the value of noninvasive intracranial pressure monitoring and were treated accordingly based on their symptoms and brain CT examination. The Glasgow prognosis scores were evaluated for patients' prognosis among different types of PADBS. Results The overall accurate prognosis rate was 43.5% (30/69) and poor prognosis rate was 56.5% (39/69). The mortality rate was 31.8% (22/69). The accurate prognosis rates of mild, moderate, and severe intracranial hypertension patients were 90.1% (10 / 11), 65.22% (15/23), and 14.29% (5/35), respectively. The accurate prognosis of patients with mild intracranial hypertension was significantly higher than that of moderate and severe intracranial hypertension. The difference was statistically significant (P<0.05). The proportion of death in patients with severe intracranial hypertension was significantly higher than that in patients with mild to moderate intracranial hypertension; the difference was statistically significant (P<0.05). Conclusion The value of noninvasive intracranial pressure monitor was closely related to the prognosis of PADBS patients. Continuous monitoring can provide an important indicator for the treatment of posttraumatic acute diffuse brain swelling.
刘宇,肖灿,石磊,张佳兴,罗嫩苗,陈静. 无创颅内压监测对治疗创伤性急性弥漫性脑肿胀的临床价值[J]. 医学临床研究, 2017, 34(5): 863-865.
LIU Yu, XIAO Can, SHI Lei,et al. Clinical Value of Noninvasive Intracranial Pressure Monitoring in the Treatment of Traumatic Acute Diffuse Brain Swelling. JOURNAL OF CLINICAL RESEARCH, 2017, 34(5): 863-865.