Abstract: Objective To investigate the effect of Shenkang injection on the clinical efficacy and the level of inflammatory factors in patients with chronic glomerulonephritis treatment. Methods Eighty-four cases of patients with chronic nephritis were random divided into two groups, 42 cases in each. The control group was treated with valsartan. On the basis of the control group, the observation group was treated with Shenkang injection. After three months of treatment, the clinical curative effect and TCM symptom integral, inflammatory factors and renal function were compared between the two groups. Results After 3 months of treatment, the total effective rate of the observation group was 83.33%(35/42), which was significantly higher than that of the control group 61.90%(26/42) (P<0.05); The 24hUPr,β2-MG ,TNF-α, IL-6 and IL-8 in the observation group were significantly lower than those in the control group (P<0.05);The TCM symptom score of the observation group was significantly lower than that of the control group and there was significant difference between the two groups (P<0.05). Conclusion Shenkang injection can improve the clinical curative effect of chronic nephritis patients, improve renal function and clinical symptoms, reduce inflammation with less adverse reactions, it is worthy of attention.
孔淑敏,沈华英. 肾康注射液治疗慢性肾炎患者的近期疗效及对炎症因子水平的影响[J]. 医学临床研究, 2017, 34(5): 833-835.
KONG Shu-min, SHENG Hua-ying. Effect of Shenkang Injection on the Clinical Efficacy and the level of Inflammatory Factors in Patients with Chronic Glomerulonephritis. JOURNAL OF CLINICAL RESEARCH, 2017, 34(5): 833-835.