<sup>18</sup>F-FDG PET/CT最大标准化摄取值与口腔鳞状细胞癌临床病理特征的相关性分析

doi:10.3969/j.issn.1671-7171.2017.03.035

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摘要【目的】探讨口腔鳞状细胞癌¹⁸F-FDGPET/CT最大标准化摄取值(SUVmax)与其临床病理特征的相关性。【方法】回顾性分析104例术前行PET/CT检查的口腔鳞状细胞癌患者的临床资料,对可能影响原发肿瘤SUVmax的相关因素,包括性别、年龄、吸烟史、肿瘤位置、肿瘤大小、TNM分期、T分期、N分期进行单因素分析和多元回归分析。【结果】口腔鳞状细胞癌患者不同分化程度、TNM分期、T分期、N分期间SUVmax比较,结果表明:分化越低、病理分期越晚者SUVmax越高,差异有统计学意义(P＜0.05)。不同性别、有无吸烟史、肿瘤部位不同对SUVmax影响比较,差异无统计学意义(P＞0.05)。经拟合曲线分析,口腔鳞状细胞癌患者SUVmax与肿瘤大小呈显著正相关性(r=0.808,P=0.000);与年龄无显著相关性(r=0.039,P=0.696)。多元线性回归分析显示肿瘤大小、TNM分期、T分期是口腔鳞状细胞癌SUVmax的独立影响因素(均P＜0.05)。其原发肿瘤SUVmax对肿瘤侵犯周围组织有预测价值,以7.98为界值时诊断效率最高,敏感度为90.0％,特异度为76.2％。【结论】口腔鳞状细胞癌¹⁸F-FDGPET/CT SUVmax在肿瘤较大、TNM分期及T分期较晚时较高,其原发肿瘤SUVmax值可预测原发肿瘤侵犯周围组织的风险。

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	郑冬牛力璇
	田嘉禾
	费军
	赵亮
	李科

关键词 ：体层摄影术, X线计算机, 体层摄影术, 发射型计算机, 氟脱氧葡萄糖F18, 口腔肿瘤/病理学, 肿瘤, 鳞状细胞/病理学

收稿日期: 2016-10-20

PACS:

R739.8

引用本文:

郑冬牛力璇;田嘉禾;费军;赵亮;李科. ¹⁸F-FDG PET/CT最大标准化摄取值与口腔鳞状细胞癌临床病理特征的相关性分析[J]. 医学临床研究, 2017, 34(3): 524-528.

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http://www.jcr.net.cn/CN/10.3969/j.issn.1671-7171.2017.03.035 或 http://www.jcr.net.cn/CN/Y2017/V34/I3/524

[1] Chen W,Zheng R,Baade PD,et al. Cancer statistics in China, 2015[J].CA Cancer J Clin,2016,66(2):115-132.
[2] Siegel RL, Miller KD, Jemal A. Cancer statistics,2016[J]. Cancer J Clin,2016,66(1):7-30.
[3] Kim H, Na K, Choi J,et al. Feasibility of FDG-PET/CT for the initial diagnosis of papillary thyroid cancer[J].Eur Arch Otorhinolarygol,2016,273(6):1569-1576.
[4] Arslan E, Cermik T,Trabulus F,et al. The contribution of FDG PET/CT in diagnosis and staging of breast cancer [J]. Eur J Nucl Med Mol,2015,42(Suppl 1):S629-S630.
[5] Groheux D, Biard L, Giacchetti S, et al. ¹⁸F-FDG PET/CT for the early evaluation of response to neoadjuvant treatment in triple-negative breast cancer: Influence of the chemotherapy regimen [J]. J Nucl Med, 2016, 57(4): 536-543.
[6] Annunziata S, Cuccaro A, Calcagni ML, et al. Interim FDG-PET/CT in Hodgkin lymphoma: the prognostic role of the ratio between target lesion and liver SUVmax (rPET) [J]. Ann Nucl Med,2016,30(8):588-592.
[7] Yesuratnam A, Wiesenfeld D, Tsui A, et al. Preoperative evaluation of oral tongue squamous cell carcinoma with intraoral ultrasound and magnetic resonance imaging - Comparison with histopathological tumour thickness and accuracy in guiding patient management[J]. Int J Oral Maxillofac Surg,2014,43(7):787-794
[8] 解明,刘颖刚,马鹏飞,等.舌癌的CT和MRI诊断[J]. 中国CT和MRI杂志,2013,11(1):37-39.
[9] Wensing B, Deserno W, Debondt B, et al. Diagnostic value of MR Lymphangiography in preoperative staging of clinically negetive neck in squamous cell carcinoma of the oral cavity[J]. Eur Arch Otorhinolarygol,2012,269(4): 1324-1332.
[10] Kazuhiro K, Kayo S , Michio S, et al. FDG-PET/CT for diagnosis of primary ovarian cancer [J]. Nucl Med Commun, 2011,32(7):549-553.
[11] 王跃涛,刘德峰,钱作宾,等.¹⁸F-FDG PET／CT双时相显像对肺部病灶的定性诊断价值.中华核医学杂志,2009,29(5):293-296.
[12] Dylan J, Hazem A, David G,et al. Histological grade/differentiation and 18-FDG PET/CT in oesophageal cancer[J]. Gastroenterol,2013, 144(5): 515-519.
[13] 秦琛,马学真.¹⁸F-FDG PET/CT 标准摄取值与 NSCLC临床病理因素的关系[J].齐鲁医学杂志,2009,24(2):104-105.
[14] 刘德军,冯彦林,余丰文,等.非小细胞肺癌组织学类型和分化程度对¹⁸F-FDG PET／CT标准摄取值的影响[J].中华核医学杂志,2010,30(1):5-9.
[15] 赵世俊,吴宁,郑容,等.¹⁸F-脱氧葡萄糖正电子发射计算机断层扫描最大标准化摄取值与非小细胞肺癌临床病理特征的关系[J].中华肿瘤杂志,2013,35(10):754-757.
[16] Nakamura K,Kodama J,Okumura Y, et al.The SUVmax of ¹⁸F-FDGPET correlates with histological grade in endometrial cancer[J].Int J Gynecol,2010,20(1):110-115.
[17] Kazuhiro K,Masato K,Kayo S,et al. Prognostic significance of SUVmax (maximum standardized uptake value) measured by ¹⁸F-FDGPET/CT in endometrial cancer[J]. Eur J Nucl Med Mol,2012, 39(5):840-845.