Abstract：【Objective】To analyze the changes of blood pressure variability and ambulatory blood pressure in patients with hypertension and coronary heart disease.【Methods】Clinical data of 160 patients with hypertension in our hospital from June 2014 to June 2015 were selected.According to the results of coronary angiography (CGA) or coronary CT imaging (CTA), the patients were divided into coronary heart disease with hypertension (n=80, the observation group) and single hypertension group (n=80, the control group). The dynamic blood pressure and blood pressure variability were compared between the two groups.【Results】In the observation group, daytime average systolic blood pressure, nighttime average systolic blood pressure, 24h mean systolic blood pressure, daytime average pulse pressure, nighttime average pulse pressure, 24h average pulse pressure, daytime average systolic blood pressure standard deviation, average nighttime systolic blood pressure standard deviation, 24h average systolic blood pressure standard deviation were significantly higher than those in the control group, the difference was statistically significant (all P<0.05); in the comparison of the daytime average diastolic blood pressure, nighttime average diastolic blood pressure, 24h mean diastolic blood pressure, daytime average diastolic blood pressure standard deviation, average nighttime diastolic blood pressure standard deviation and 24h mean diastolic blood pressure standard deviation , there were no significant differences in the two groups(P>0.05).【Conclusion】Patients with hypertension complicated with coronary heart disease have more dynamic blood pressure fluctuation,and the blood pressure variability increases correspondingly.To strengthen the monitoring of ambulatory blood pressure and blood pressure variability has a certain role in the diagnosis and treatment of coronary heart disease with hypertension.
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2017, Vol. 34 
