血清性激素水平在不孕症患者中的表达及意义

doi:10.3969/j.issn.1671-7171.2017.03.026

摘要
图/表
参考文献
相关文章 (15)

全文: PDF (0 KB) HTML (1 KB)
输出: BibTeX | EndNote (RIS)

摘要【目的】探讨血清中性激素水平在不孕症患者中的表达及意义。【方法】选取2013年8月至2015年12月在本院收治的不孕症患者48例(观察组),同时选取在本院进行健康体检妇女30例(健康对照组),比较两组患者血清性激素相关指标如促黄体生成素( luteinizing hormone,LH)、促卵泡成熟激素( FSH)、睾酮(Testosterone,T) 、孕酮( Progesterone,P)、雌二醇(estradiol, E₂)、泌乳素( prolactin,PRL)及相关抗体如抗子宫内膜抗体( Endometrial antibody,EMAb ) 、抗精子抗体( Antisperm antibody,AsAb) 、抗透明带抗体( Anti zona pellucida antibodies,AzpAb)、抗卵巢抗体( antiovary antibody,AoAb)表达水平。【结果】与对照组对比,观察组T、PRL水平明显升高,P、E₂水平明显降低(P<0.05);与对照组对比,观察组EMAb、AsAb、AzpAb、AoAb阳性表达率明显升高(P<0.05)。【结论】不孕症患者的血清T、PRL水平增高、P、E₂水平下降,故检测血清中上述性激素和免疫抗体的变化对不孕症患者的诊治具有重要的临床指导意义。

	服务

	把本文推荐给朋友
	加入我的书架
	加入引用管理器
	E-mail Alert
	RSS
	作者相关文章
	李海燕
	余灵辉
	曹登成

关键词 ：性腺甾类激素/血液, 不育, 女(雌)性, 促黄体激素, 睾酮, 孕酮, 雌二醇

Abstract：【Objective】 To investigate the clinical value of the detection of serum donadal hormone levels in the diagnosis and treatment of infertility. 【Methods】A total of 48 cases of infertility patients from August 2013 to December 2015 in our hospital constituted the observation group. At the same time, 30 cases of healthy women were selected as the healthy control group. The expression levels of serum sex hormone related factors such as luteinizing hormone (LH), follicle-stimulating hormone (FSH), testosterone (T), progesterone (P), estradiol (E₂), Prolactin (PRL) and related antibodies such as endometrial antibody (EMAb), antisperm antibody (AsAb), anti zona pellucida antibodies (AzpAb), anti-ovarian Antibody (antiovary antibody, AoAb) were observed and compared between the two groups. 【Results】Compared to the control group, the T and PRL levels of the observation group were significantly increased, P and E2 levels were significantly reduced (P<0.05); while EMAb, AsAb, AzpAb and AoAb positive expression rate was significantly higher (P<0.05). 【Conclusion】 Sex hormone levels and positive expression of related antibodies have important clinical significance in the diagnosis and treatment of infertility patients.

Key words： Gonadal Steroid Hormones/BL Infertility, Female Luteinizing Hormone Testosterone Progesterone Estradiol

收稿日期: 2016-09-01

PACS:

R711.6

引用本文:

李海燕;余灵辉;曹登成. 血清性激素水平在不孕症患者中的表达及意义[J]. 医学临床研究, 2017, 34(3): 496-498,501.
LI Hai-yan, YU Ling-hui, CAO Deng-cheng. Expression and Significance of Gonadal Hormone Levels in Infertility Patients. JOURNAL OF CLINICAL RESEARCH, 2017, 34(3): 496-498,501.

链接本文:

http://www.jcr.net.cn/CN/10.3969/j.issn.1671-7171.2017.03.026 或 http://www.jcr.net.cn/CN/Y2017/V34/I3/496

[1] 林静华,张娟,蔡乐山.血清性激素测定对女性不孕症的诊断价值[J].中国校医,2013,29(5):370-372.
[2] 张群芝,张静.不孕与子宫内膜的病理变化的相关性分析[J].中国妇幼杂志,2013,28(17):2751-2752.
[3] 黄茜,邹彦,刘峰.女性不孕症病因及相关因素的研究进展[J].检验医学与临床,2011,8(3):82-84.
[4] 叶文,刘凤霞,任小川.性激素六项水平对不孕症诊断价值分析[J].中国性科学,2015,24(9):89-91.
[5] 刘利利,王玫,任景芳,等.注射用醋酸亮丙瑞林微球治疗子宫腺肌病合并不孕60例临床观察[J].医学临床研究,2015,32(1):87-89.
[6] Fu B, Lun X, Gong Y. Effects of the combined therapy of acupuncture with herbal drugs on male immune infertility-a clinical report of 50 cases [J].J Tradit Chin Med,2005,25(3):186-189.
[7] 王东蕾.性激素六项在原发和继发性不孕症中的临床应用价值[J].临床检验杂志(电子版),2014,3(1):534-535.
[8] 李萌.性激素检测在女性不孕症诊断中的价值分析[J].中外医疗,2014,33(3):176-177.
[9] 关亚娟.128例不孕症患者血清性激素6项临床检测分析[J].河北医学,2015,27(8):1544-1546.
[10] 王红.生殖免疫性抗体检测在不孕不育诊断中的意义[J].国际检验医学杂志,2014,35(9):1223-1224.
[11] 胡丽梅,陆国健.女性不孕症患者的激素指标特征与临床诊断价值分析[J].检验医学与临床,2014,11(15):2135-2136.
[12] 海燕.性激素测定对不孕症妇女诊断的价值及临床意义[J].河北医学,2012,18(4):518-519.
[13] 刘宏明,蒋显勇,陈春玲,等.电化学发光法检测不孕症血清性激素水平的变化[J].中外医疗,2013,32(13):168-168.
[14] 赵晓霞,张海梅.泼尼松联合维生素治疗女性免疫性不孕的临床观察[J].山西医药杂志,2015,44(4):418-420.
[15] 杨晓珊,陈泽微,李格宁.性激素六项检查在女性不孕症诊断中的临床意义[J].实验与检验医学,2011,29(2):169-170.