Abstract：【Objective】To investigate the correlation between ultrasonographic features and sex hormones and insulin resistance index in patients of polycystic ovary syndrome (PCOS). 【Methods】 Ninety patients with PCOS from February 2014 to May 2016 in our hospital were selected as observation group, and 53 cases in the same period for health examination were selected as control group. Ultrasonic imaging detection was performed in the two groups of patients, the detecting indexes included ovarian total area (TA), ovarian stromal area (SA);At the same time the ratio of SA/TA was calculated, sex hormone levels, blood glucose levels and other related indicators were detected in the two groups of patients , and correlation between the sonographic characteristics and sex hormone index and the HOMA-IR of patients in the observation group was analyzed. 【Results】 Compared with the control group, the luteinizing hormone (LH), testosterone (T), estradiol (E2) and fasting blood glucose (FBG) and HOMA-IR of the observation group of patients increased significantly, the differences were statistically significant (P<0.05);compared with the control group, TA, SA and SA/TA of the observation group of patients increased significantly, the difference was statistically significant (P<0.05);Person correlation analysis showed that SA of the observation was positively correlated with LH, T, E2 significantly(r=0.280,0.610,0.389, P<0.05);SA/TA, and LH, LH, T,E2 also showed a significant positive correlation (r=0.265,0.378,0.332, P<0.05);there were significant positive correlation between TA and E2 (r=0.315, P<0.05).SA/TA ratio was positively correlated with HOMA-IR (r=0.712, P<0.05). 【Conclusion】 Ovarian SA and TA of patients with PCOS are significantly higher than those of healthy physical examination, and the ultrasonic image characteristics are significantly correlated with sex hormones and HOMA-IR.
张杰;张翔;延静;孟庆;李品群;李琼琼. 多囊卵巢综合征超声影像特征及与性激素、胰岛素抵抗指数的相关性分析[J]. 医学临床研究, 2017, 34(3): 456-458.
ZHANG Jie, ZHANG Xiang, YAN Jing,et al. Correlation between Ultrasound Imaging Features and Sex Hormones/ Insulin Resistance Index in Polycystic Ovary Syndrome. JOURNAL OF CLINICAL RESEARCH, 2017, 34(3): 456-458.
[1] 戴蓓蓓,任芸芸,孙 莉,等.不同表现多囊卵巢综合征超声参数与内分泌指标的相关性研究[J].中华超声影像学杂志,2014,23(7):609-613. [2] 刘秋颖,王璐璐,张云山,等.速度向量成像技术评价多囊卵巢综合征患者颈动脉弹性[J].中国介入影像与治疗学,2013,10(9):531-535. [3] 周毓青.超声在多囊卵巢综合征诊疗中的应用[J].诊断学理论与实践,2012,11(3):214-218. [4] 陈慧,詹维伟,陈晨,等.不同分型多囊卵巢综合征患者的超声特征及其与内分泌指标的相关性[J].中华医学超声杂志(电子版),2013,10(9):763-768. [5] 晏群,洪 洁,顾卫琼,等.多囊卵巢综合征患者代谢综合征患病风险研究[J].中华内分泌代谢杂志,2010,26(5):351-354. [6] 陈慧,詹维伟,杨志芳,等.伴或不伴胰岛素抵抗的多囊卵巢综合征的超声特征及其与内分泌指标的相关性[J].中国医学影像技术,2014,30(4):595-599. [7] 张慧英,张艳芳,韩玉崑,等.多囊卵巢综合征患者子宫内膜组织中胰岛素PI3K/Akt 信号通路的活化及其意义[J].中华妇产科杂志,2012,47(1):19-23. [8] 缪琳,石 娟,洪 洁,等.低浓度性激素结合球蛋白与代谢综合征的发生相关[J].中华内分泌代谢杂志,2013,29(6):494-497. [9] Villavicencio A, Aguilar G, Argüello G,et al.The effect of overweight and obesity on proliferation and activation of AKT and ERK in human endometria[J].Gynecol Oncol,2010, 117(1): 96-102. [10] Li R,Zhang Q,Yang D,et al.Prevalence of polycystic ovary syndrome in women in China: a large community-based study[J].Hum Reprod,2013,28(9):2562-2569.
2017, Vol. 34 
