Abstract：【Objective】 To observe the effects of different anesthesia methods on physiological and biochemical changes in patients undergoing bronchoalveolar lavage (BAL) under mechanical ventilation . 【Methods】A total of 80 cases who underwent BAL under mechanical ventilation in ICU were selected as study subjects and were randomly divided into two groups, 40 cases in each group. The control group were treated with lidocaine surface anesthesia, while the observation group were treated with lidocaine surface anesthesia combined with fentanyl anesthesia. The changes of heart rate, blood pressure, body temperature, blood gas parameters and biochemical indicators were compared between the two groups after operation. 【Results】 There were no significant differences between the two groups at the beginning of anesthesia, after 10min, 20min and 30min of anesthesia and at the end of anesthesia (P>0.05). The blood gas indexes showed no significant difference between the two groups before operation (P>0.05). After operation, the PH , PaCO2, PaO2 and SaO2 in the control group were significantly decreased (P<0.05), and the blood gas indexes in the observation group were higher than those in the control group after operation (P<0.05). The blood biochemical indexes showed no significant differences between the two groups before operation (P>0.05). After operation, Hb, PLT,HCT, ALT and AST in the two groups were decreased, and the above indexes in the observation group were higher than those in the control group (P<0.05). 【Conclusion】Compared with the lidocaine surface anesthesia alone, lidocaine plus fentanyl can better maintain the vital signs, the blood gas indexes and biochemical indexes in the patients undergoing BAL under mechanical ventilation.
赵金霞. 不同麻醉方式对机械通气下BAL患者生理与生化指标的影响[J]. 医学临床研究, 2017, 34(2): 288-290.
ZHAO Jing-xia. Effect of Different Anesthesia Methods on Physiological and Biochemical Changes in Patients Undergoing BAL under Mechanical Ventilation. JOURNAL OF CLINICAL RESEARCH, 2017, 34(2): 288-290.
2017, Vol. 34 
