Abstract：【Objective】To study the clinical characteristics and analyze the possible reasons for acute ischemic stroke with early stage negative magnetic resonance diffusion-weighted imaging (DWI) detection.【Methods】Three cases of acute ischemic stroke with early negative magnetic resonance diffusion-weighted imaging were collected from January 2014 to February in our hospital and the clinical characteristics were retrospectively analyzed.【Results】Among the three cases, the magnetic resonance diffusion-weighted imaging of the first case was negative 7 hours after onset of disease, while the diffusion weighted imaging show positive of dorsolateral medulla oblongata recent infarction 64 hours after onset. The diffusion-weighted imaging of the second case was negative 6 hours after onset of disease, while the diffusion-weighted imaging showed positive of recent infarction on the right side of basal ganglia 52 hours after onset, which was 28 hours after the symptoms aggravated. The diffusion-weighted imaging of the third case was negative 5 hours after onset of disease, while the diffusion weighted imaging showed positive of right dorsal medulla oblongata recent infarction 64 hours after onset.【Conclusion】Magnetic resonance diffusion-weighted imaging is an effective tool in diagnosing acute ischemic stroke in the early stage, which shows positive image within a few minutes after onset. However, we noticed that there are the large number of acute ischemic stroke patients with DWI negative in early stage and that some DWI positive image can show up to 120 hours after onset. Therefore, when DWI is negative while the acute ischemic stroke symptoms are present, we should do the proper treatment and re-examine DWI in order to make early diagnosis and reduce misdiagnosis or missed diagnosis.
王继蕊;孙丽红;张元超;朱璐;刘婧婷;商秀丽. 磁共振DWI早期呈阴性的急性缺血性脑卒中的临床特点及原因分析[J]. 医学临床研究, 2017, 34(2): 264-268,271.
WANG Ji-rui; SUN Li-hong; ZHANG Yuan-chao,et al. Clinical Characteristics Analysis of Acute Ischemic Stroke with Early Stage Negative Magnetic Resonance Diffusion-Weighted Imaging. JOURNAL OF CLINICAL RESEARCH, 2017, 34(2): 264-268,271.
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