Abstract:【Objective】 To investigate the clinical features, MRI image representation and curative effect of deep infiltrating endometriosis (DIE). 【Methods】 Clinical data of 85 patients with endometriosis diagnosed in our hospital from February 2014 to February 2016 were retrospectively analyzed, including the clinical, MRI imaging and treatment. The clinical features of DIE were compared with those of non DIE group, and the MRI imaging findings and therapeutic effects of DIE were observed.【Results】40 cases in 85 patients were confirmed with DIE pathologically, the incidence of severe dysmenorrhea and dyspareunia, adnexal cyst activity, uterosacral ligament nodules of the DIE group were 92.5%, 65%,72.5%, 67.5% ,which were significantly higher than those in the non DIE group (n=45) 33.3%, 11.1%, 42.2%,17.8%. The difference was statistically significant (P<0.05). 5 cases of vaginal rectum nodules were found in the DIE group, posterior fornix blue nodules in 15 cases, but none of them were found in the non DIE group. MRI showed that accumulated uterine uterosacral ligament were found in 27 cases (uterosacral ligament thickening, asymmetry or ligament nodules); T1WI, T2WI sequences are mainly high signal. The total effective rate of treatment was 90.6%. The clinical symptom score and CA125 level 6 months after the operation were significantly lower than those before operation (P<0.05) . 【Conclusion】 The typical clinical symptoms of patients with DIE are severe dysmenorrhea and dyspareunia. Rectovaginal nodules and posterior fornix blue nodules are sensitive manifestations for diagnosis of DIE; MRI can accurately display the range of DIE, which plays an important role in preoperative diagnosis of DIE. According to the clinical symptoms and MRI results, the effect of corresponding treatment methods will be good.