Abstract：【Objective】To explore the clinical effects of diseased segment fixation in the treatment of patients with spinal tuberculosis. 【Methods】Retrospectively 84 cases with spinal tuberculosis in our hospital from January 2009 to December 2014 were analyzed according to different operation methods , and they were divided into diseased segment fixation group (fixed in lesions involving individual neurons, 38 cases) and non-diseased segment fixation group (using long and short segmental fixation, 46 cases). The intraoperative blood loss, operative time during the surgery, the ESR and preoperative and postoperative CRP level , CRP ,VAS score, Franke l classification and Cobb Angle of the two groups were observed and analyzed.【Results】Blood loss and operation time of diseased segment fixation group were superior than diseased non-segment fixation group, the difference was statistical significance (P<0.05); ESR and CRP of two groups reduced to normal levels 6 months after surgery, but there was no statistical difference between two groups(P＜0.05).VAS score at the last follow-up of the two groups were decreased ,and VAS score of the diseased segment fixation group was lower than that of the non-diseased segment fixation group (P<0.05);The Frankel function classification of the two groups were obviously recovered ;Cobb angle at the last follow-up of the two groups were less than that before surgery, but the correction of Cobb's angle and angle loss of preoperative and postoperative and the last follow-up of two groups were not statistically different. 【Conclusion】Diseased segment fixation in the treatment of patients with spinal tuberculosis is a safe and effective therapy, which can effectively preserve normal vertebral motion nerve unit adjacent to diseased segment with its advantage of less intraoperative bleeding and shorter operation time.
杨帆;韩翠玉;杨雯;侯煜;孙博;梁志兴;申志坤. 病椎间固定在脊柱结核患者治疗中的应用价值[J]. 医学临床研究, 2016, 33(12): 2335-2339.
YANG Fan, HAN Cui-yu, YANG Wen,et al. Clinical Effects of Diseased Segment Fixation in Treatment of Patients with Spinal Tuberculosis. JOURNAL OF CLINICAL RESEARCH, 2016, 33(12): 2335-2339.
2016, Vol. 33 
