Abstract：【Objective】To investigate the value of dynamic threedimensional contrastenhanced ultrasonography (3DCEUS) in the diagnosis of hepatocellular carcinoma. 【Methods】Clinical and imaging data of 50 patients with hepatocellular carcinoma admitted in our hospital from June 2014 to December 2015 were retrospectively analyzed. Each patient underwent 3DCEUS and contrastenhanced computed tomography (CECT). The image quality of the two methods, including the internal display of the arterial phase (enhancement mode, the internal blood vessels of the tumor), the blood vessels of the tumor vessels, and the display of the tumor boundary were comprehensively scored.【Results】 After the injection of the contrast agent, 50 cases of tumor 3DCEUS were given different degrees of enhancement. The results showed that: According to 3DCEUS, 3 cases received scores of 0, 10 cases received scores of 1, and 37 cases received scores of 2 while according to CECT, no cases received scores of 0, 9 cases received scores of 1, and 41 cases received scores of 2. Further analysis of internal display of tumor of the 32 cases of patients receiving an average score of 2 using the two methods showed that there was no statistical difference between the 3DCEUS and CECT images in the enhancement mode (P>0.05); the Kappa value of the consistency score was 0.88. In the aspect of blood vessels in the tumor, 3DCEUS was superior to CECT (P<0.05). In the aspect of arteries, the two methods were not completely consistent. Images with scores of 0 and 1 showed no statistically significant difference between 3DCEUS and CECT (P>0.05), while for images with scores of 2, 3DCEUS was superior to CECT (P<0.05). In the aspect of relationship between peripheral tissues, the two methods showed no significant difference (P>0.05).【Conclusion】Dynamic 3DCEUS had high imaging quality in hepatocellular carcinoma diagnosis, and shows the enhancement way and boundary of hepatocellular carcinoma clearly as well as CECT does. In addition, the ability of 3DCEUS in displaying tumor internal vessels and supplying vessels was superior to that of CECT.
王鑫 李玲. 动态三维超声造影对肝细胞癌的超声诊断价值[J]. 医学临床研究, 2016, 33(9): 1702-1707.
WANG Xin,LI ling. Evaluation of the Imaging Quality of Dynamic ThreeDimensional ContrastEnhanced Ultrasonography in the Diagnosis of Hepatocellular Carcinoma. JOURNAL OF CLINICAL RESEARCH, 2016, 33(9): 1702-1707.
2016, Vol. 33 
