Abstract:【Objective】To investigate the application value of lung computer tomography angiography (CTA) in the diagnosis of pulmonary embolism (PE). 【Methods】Clinical data and CTA data of 67 cases of suspected PE patients in our hospital received during December 2013 to December 2015 were retrospectively analyzed. Comprehensive analysis of CTA imaging features, clinical manifestations, misdiagnosis, and embolus characteristics of pulmonary embolism were conducted based on the pathological examination. 【Results】There were 67 cases of suspected PE, in which 63 cases of PE were diagnosed by CTA and 62 PE patients were diagnosed pathologically. So the misdiagnosis rate of PE by CTA was only 1.58%, and there were no missed diagnosis. Among the 62 cases of patients with PE, 9 cases were of multisite embolism in pulmonary trunk, leaves, segment pulmonary, 12 cases involving the main pulmonary artery, 34 cases involving the right pulmonary artery, and 22 cases involving the left pulmonary artery. There were 78 emboli total among the 62 cases, include thrombosis (59), fat plugs (11), air plugs (5) and others (3). Thrombosis came from different places, such as pelvic thrombosis (24) and lower extremity deep venous thrombosis (19). 【Conclusion】CTA in the diagnosis of pulmonary embolism not only can display the position, shape, duration time, and indirect signs of embolus, but also can diagnose a disease that shows similar symptoms to PE. CTA is an intuitive and reliable method for diagnosing PE that has a low rate of misdiagnoses and missed diagnoses. It also can help find the source of emboli, which may provide the basis for clinical thrombolytic therapy.