Abstract:【Objective】To evaluate the efficacy of the vermilion tubercle square flap on vermilion reconstruction of unilateral cleft lips.【Methods】Eighty three cases of unilateral cleft lip were selected. 36 cases of them were incomplete cleft lip , and 49 cases were of complete cleft lip. 85 cases were randomly divided into two groups according to the admission: 40 cases for Group A, whose vermilion were reconstructed by the vermilion tubercle square flap; and 45 cases for Group B, to which the "Z" shape exchange method was used to repair the vermilion lips. Comparison of repair effect of the vermilion in the two groups was made in 7 d and 1~2 years after surgery .The contents included the indexes as whether the suffered lip was too thick or too thin, whether there was a whistling deformities and whether there was a sharp lip peak or discontinuous Cupid's bow.【Results】All wounds in 80 cases were healed at Phase One, only 5 cases had nasal floor infection. No necrosis nor infection occurred in all vermilion turning to flaps. In 1 ~ 2 years after the surgery ,the incidence of overthickness or overthinness of vermilion, sharp lip peak and discontinuous percentage of Cupid's bow in the Group A were significantly lower than those of the Group B, and the differences were statistically significant (P<0.05); But there was no significant difference in whistling deformities between the two groups (P>0.05).【Conclusion】The vermilion tubercle square flap for unilateral cleft lips is a good method to repair and reconstruct lip vermilion, lip peak and vermilion tubercle shape of patients with cleft lip. It is worthy of clinical popularization and application.