Abstract：【Objective】To discuss and analyze the risk factors of ventilator associated pneumonia (VAP) in patients in the intensive care unit and possible preventative measures. 【Methods】Sixtyone patients underground mechanical ventilation treatment in our hospital's intensive care unit from May 2014 to May 2015 were chosen as the study subjects. The patients were divided into two groups according to whether or not the patients had VAP. The first group had ventilator associated pneumonia (VAP) and the second group of did not have ventilator associated pneumonia (VAP). The clinical data of the two groups were observed and compared. Single factor analysis and multivariable analysis were made regarding VAP in the patients. 【Results】The single factor analysis showed that age, gender and incidence of anemia were not statistically different between the two groups (P>0.05). However, there were statistically significant differences (P<0.05) in terms of antimicrobial drug use time, invasive operation, mechanical ventilation time, acute physiology and chronic health evaluation system Ⅱ (APACHE Ⅱ), respiratory immune dysfunction, incidence of gastrointestinal reflux and aspiration, and pipe pollution events . Logistic regression analysis also showed that an APACHE Ⅱ of 15 points or above, mechanical ventilation time of more than 7 days, pipe pollution, invasive operation, lower immune function of respiratory, incidence of gastrointestinal reflux and aspiration were risk factors of ventilator associated pneumonia in the intensive care unit (P<0.05). 【Conclusion】A mechanical ventilation time of more than 7 days, an APACHE Ⅱ score of more than 15, use of an invasive operation, respiratory immunocompromised, pipe pollution, and gastrointestinal reflux and aspiration are the intensive care unit risk factors of ventilator associated pneumonia. Medical staff should pay attention to the actual situation of patients with these risk factors and take corresponding prevention and control measures.
袁烁 张威威. 重症监护室呼吸机相关性肺炎的相关危险因素及其预防措施[J]. 医学临床研究, 2016, 33(6): 1069-1072.
YUAN Shuo,ZHANG Weiwei. Analysis of the Risk Factors of Ventilator Associated Pneumonia (VAP) in Intensive Care Unit. JOURNAL OF CLINICAL RESEARCH, 2016, 33(6): 1069-1072.
2016, Vol. 33 
