Abstract：【Objective】To collect and summarize the perioperative data and information of infants undergoing rapid twostage arterial switch operation (ASO).【Methods】The data we retrospectively reviewed included 14 infants who had undergone the rapid twostage arterial switch operation (ASO). Anesthesia was maintained with sufentanil, propofol, and rocuronium infusion combined with sevoflurane inhalation during ASO. Cardiac function was maintained by dopamine, milrinone, and adrenaline infusion after the release of the aortic crossclamp. The patients were then rewarmed to 36oC, improving coagulation function and maintaining acidbase balance, before weaning off the cardiac pulmonary bypass (CPB). 【Results】Of the 14 patients who undergone the firststage preparatory operation, two died of low cardiac output syndrome (LCOS). The other 12 patients underwent the secondstage ASO. The vasoactiveinotrope score before and after ASO were 16.75 (P25, P75: 12.625, 28.375) and 22.5 (P25, P75: 15.375, 29.375), respectively. There were an additional two deaths (2/12, 16.7%) after ASO. The incident of postoperative LCO and hypoxemia were 58.3% (7/12) and 16.7% (2/12), respectively. No patients died of anesthesia.【Conclusion】The key to successful anesthesia management in rapid twostage ASO is maintaining and improving left ventricular function. It is essential to use appropriate anesthetics intraoperation as well as to strengthen myocardial contractility, to decrease afterload and pulmonary vascular resistance, and to improve coagulation function.
2016, Vol. 33 
