摘要目的探讨国产半导体激光治疗中、重度痤疮的疗效及安全性。方法将100例中、重度痤疮患者随机分为观察组（50例）和对照组（50例）。观察组给予国产半导体激光治疗（波长：650 nm和810 nm、功率：400～450 W、1次／日，10分钟／次。持续进行14 d；每二日一次，10分钟／次，持续14 d ）。对照组给予罗红霉素胶囊（2次／日，1粒／次）、维生素B620 m g／片（3次／日，2片／次）和绿药膏（2次／日，局部涂抹），持续治疗28 d。对比两组患者临床有效率；两组患者治疗过程中不良反应发生情况和消退时间；两组合患者治疗后3个月内复发情况。结果观察组治疗后有效率（82％）低于对照组（86％），但差异无统计学意义（ P ＞0．05）。观察组患者色素沉着发生率和丘疹复发率均低于对照组，差异有统计学意义（ P ＜0．05）。结论国产半导体激光技术治疗中、重度痤疮的临床效果满意，值得推广。
Abstract：[Objective] To explore the efficacy and safety of domestic semiconductor laser treatment of moderate‐to‐severe acne .[Methods]A total of 100 moderate‐to‐severe acne patients were randomly divided in‐to observation and control groups ( n=50 each) .The observation group received domestic semiconductor laser therapy (wavelength:650 and 810nm .power :400~450W ,once daily ,10 min/time for 14 day ;twice daily , 10 min/times for 14 days) .The control group received Roxithromycin Capsules (1 tablet twice daily) ,vitamin B6 tablets (2 tablets thrice daily) and green ointment (twice daily ,topical) .Clinical efficacy ,adverse events during treatment , resolution time and recurrence within 3 months after treatment were compared for two groups .[Results] The efficiency of observation group was lower than that of control group (82% vs 86% ) . The differences were not statistically significant ( P > 0 .05) .The incidence of pigmentation and recurrence rate of rash in observation group were lower than those in control group .And the differences were statistically significant ( P <0 .05) .[Conclusion] For moderate‐to‐severe acne ,the clinical efficacy of domestic semicon‐ductor laser technology is satisfactory .And it is worthy of wider promotions .
引用本文:
吕玲玲. 国产半导体激光治疗中、重度痤疮的疗效及安全性[J]. 医学临床研究, 2015, 32(1): 124-126.
LV Ling-ling. Efficacy and Safety of Domestic Semiconductor Laser Treatment of Moderate-to-severe Acne. JOURNAL OF CLINICAL RESEARCH, 2015, 32(1): 124-126.
2015, Vol. 32 
