Abstract:To explore the questionnaire scores and gastroscopic findings of gastroesophageal reflux disease(GERD) in adolescents .[Methods]Totally 51 patients with GRED in our hospital from Jan . 2010 to Jan .2014 were chosen .Other 50 concurrent patients without GRED in the same department were cho-sen as the control group .The diagnostic critical value was calculated .The diagnostic value between question-naire scores of GERD(GERDQ) and gastroscopy of GERD was compared .[Results]The distribution result of GERDQ scores of patients showed that GERDQ in GERD group was mainly 8~11 scores which the proportion of patients was 62 .7% ,while that in control group was mainly 7~9 scores which the proportion of patients was 50 .0% .There were 42 patients with positive results of gastroscopy (82 .4% ) and 9 patients with negative results(17 .6% ) in GERD group ,while there were 14 patients with positive results (28 .0% ) and 36 patients with negative results (72 .0% ) in control group .According to ROC result pf GERDQ score ,the diagnostic sensitivity and specificity were the best when the critical value was 7 .5 .The sensitivity ,specificity ,positive predictive value and negative predictive value were 84 .3% ,56 .0% ,66 .6% and 77 .4% ,respectively .[Con-clusion]Both GERDQ score and gastroscopy for the diagnosis of GERD have good effect .If the critical value of GERDQ for the diagnosis of GERD was 7 .5 and the relative gastroscopic findings are mainly LA classifica-tion A and Band in adolescents ,the pathogenetic condition of GERD in adolescents is generally milder .