Abstract:To investigate the sleep quality in patients with maintenance hemodialysis and to ex-plore the influential factors of sleep quality .[Methods]According to Pittsburg sleep quality index (PSQI) score ,99 maintenance hemodialysis patients were divided into good sleep group (PSQI≦5) and poor sleep group(PSQI<5) .The biochemical indicators between good sleep group and poor sleep group were compared . The factors affecting sleep quality was analyzed .Logistic regression method was use to analyze the relationship of clinical general data such as age and sex and biochemical indexes such as hemoglobin (Hb) and immunoreac-tive parathyroid hormone(iPTH) with sleep quality .[Results]Compared with poor sleep group ,Hb ,albumin (ALB) and Kt/V in good sleep group were increased ,while hsCRP ,iPTH ,urea ,creatinine ,sodium bicar-bonate ,calcium-phosphorus product and ferritin before dialysis were decreased .Logistic regression analysis showed that Hb(OR=1 .051 ,P =0 .003) ,ALB(OR=1 .209 ,P =0 .014) ,iPTH(OR=0 .998 ,P =0 .043) and calcium-phosphorus product(OR=0 .94 ,P=0 .003) were associated with sleep quality of patients .[Con-clusion]Sleep quality of hemodialysis patients is commonly decreased .Hb ,ALB ,iPTH and calcium-phos-phorus product may be associated with sleep quality of patients .Recognition and control of sleep quality should be strengthened so as to improve the sleep and increase quality of life of patients .