Abstract:To observe the effect of autogenous blood salvage (BS ) on blood protection and small intestinal microcirculation in patients undergoing spine surgery .[Methods] A total 40 ASA Ⅰ ~ Ⅱ pa-tients scheduled for spine surgery under general anesthesia were randomly divided into autogenous BS group (group Ⅰ) and xenogenous blood transfusion group(group Ⅱ) .Blood loss ,xenogenous blood transfusion vol-ume and the expressions of intestinal fatty acid binding protein (I-FABP) and D-lactate before operation (T1 ) , 30min after tracheal intubation(T2 ) ,at the end of operation(T3 ) and 24h after operation(T4 ) were recorded in two groups .[Results]Compared with group Ⅰ ,xenogenous blood transfusion volume in group Ⅱ increased and the expressions of I-FABP and D-lactate in group Ⅱ at T3 and T4 time points increased .[Conclusion]Au-togenous BS can effectively reduce xenogenous blood transfusion during spine surgery ,and has less effect on small intestinal microcirculation perfusion .