Abstract:Objective To retrospectively analyze "exudative change"of ocular fundus examined by RetCam II .[Methods] The overall fundus photography with RetCam II after mydriasis under superficial anesthesia were per-formed in 12186 infants for screening out fundus "exudative change".Cases were counted for obtaining the per-centage .[Results] Fundus "exudative change"of 489 patients(4 .01% ) were found .The punctiform effusion was the most common .In eye diseases ,there were 202 retinopathy of prematurity (ROP)(41 .31% ) ,12 familial exuda-tive vitreoretinopathy (2 .45% ) ,8 Coats disease(1 .64% ) and 2 Norrie disease(0 .40% ) .In original diseases ,there were 176 cytomegalovirus infection(36 .00% ) ,10 neonatal asphyxia(2 .04% ) ,8 anemia(1 .64% ) ,8 septicemia (1 .64% ) and 63 other diseases(12 .88% ) .[Conclusion]"Exudative change" not only occurs in eye diseases ,but also occurs in children with systemic diseases .Because infants do not cooperate the examination ,RetCam II is the best choice in order to avoid the missing of peripheral retinopathy .