Abstract:To explore the influential factors of nonalcoholic fatty liver disease (NAFLD ) among Chinese people in order to provide the evidence basis for the prevention and control of NAFLD .[Methods] Key-words such as'NAFLD','risk factors','influential factors'and'case-control'were searched from in CNKI ,WanFang , VIP ,CBM ,PubMed and EMbase databases between database establishment and Dec .2012 .The studies about NAFLD among Chinese people were collected .Meta-analysis method was used to obtain a comprehensive and quantitative assessment of the risk factors of NAFLD .[Results]The 21 literatures were enrolled in the study .The total number of cases and controls were 7546 and 27065 ,respectively .The OR values for obesity ,male ,hyper-triglyceridemia ,elevated low-density lipoprotein cholesterol(LDL) ,hypertension ,waist ,hyperglycemia ,elevated diastolic blood pressure(DBP) ,age and elevated alanine transaminase(ALT) were more than 1 ,while the OR val-ues for high-density lipoprotein cholesterol(HDL) and physical exercise were less than 1 .[Conclusion] The major risk factors for NAFLD among Chinese people are obesity ,male ,hypertriglyceridemia ,elevated LDL ,hyperten-sion ,abnormal waist ,hyperglycemia ,elevated DBP ,age and elevated ALT .The protective factors of NAFLD are HDL and physical exercise.
引用本文:
陈小芳%王惠平%周滔. 中国人群非酒精性脂肪肝发病影响因素的Meta分析[J]. 医学临床研究, 2014, 31(7): 1273-1277.
CHEN Xiao-fang%WANG Hui-ping%ZHOU Tao. A Meta-analysis of the Influential Factors of Nonalcoholic Fatty Liver Disease in Chinese People. 医学临床研究, 2014, 31(7): 1273-1277.