Abstract:[Objective]To observe the efficacy and safety of yanhuning combined with cimetidine or ribavi-rin for the treatment of mumps in order to provide the basis for clinical optimal medication.[Methods]A total of pediatric patients with mumps were randomly divided into observation group(n=33)and control group(n=32).All patients in two groups were treated with yanhuning 10mg/(kg·d)by intravenous drip.The ob-servation group was additionally treated with cimetidine 15~20mg/(kg·d),while the control group was addi-tionally treated with ribavirin 10~15mg/(kg·d).Clinical efficacy and safety of two groups 5d after treatment were observed.[Results]The fever clearance time and swollen extinction time in observation group were shor-ter than those in control group,and there was significant difference(P<0.05).Clinical total effective rate of observation group was 93.94%,which was higher than that of control group(75.00%)(P <0.05).There was no significant difference in the complication rate between two groups(P>0.05).No obvious adverse re-action occurred.[Conclusion]Yanhuning combined cimetidine for the treatment of mumps is more safe and ef-fective than yanhuning combined with ribavirin,so it is worthy of clinical application.
引用本文:
肖跃兵. 炎琥宁分别联合合西咪替丁与利巴韦林治疗流行性腮腺炎的疗效比较[J]. 医学临床研究, 2014, 31(5): 988-992.
XIAOYue-bing. Clinical Comparative Study of Yanhuning Combined with Cimetidine vs. Ribavirin for the Treatment of Mumps. 医学临床研究, 2014, 31(5): 988-992.