Abstract：[Objective]To explore the effect of different treatments for hydrosalpinx on the outcome of in vitro fertilization and embryo transfer(IVF-ET) .[Methods] Totally 154 patients with infertility derived from tubal causes(102 patients with a history of hydrosalpinx ) undergoing IVF-ET were collected .According to dif-ferent treatments for hydrosalpinx before IVF-ET ,all patients were divided into group A (without treatment for hydrosalpinx ,n=16) ,group B(hydrosalpinx aspiration ,n=35) ,group C(laparoscopy resection of hydro-salpinx ,n=15) ,group D(proximal tubal ligation and distal tubal salpingostomy by laparoscopy ,n =36) and group E(control group of concurrent tubal obstruction without hydrosalpinx ,n=52 ) .The dose of gonadotro-pin(Gn) ,the duration of stimulation ,estradiol(E2 ) level on HCG day ,the number of retrieved oocytes and the transferred embryo ,the fertilization rate ,pregnancy rate ,abortion rate and ectopic pregnancy rate were compared among groups .[Results] There was no significant difference in Gn dosage ,the duration of stimula-tion ,E2 level on HCG day ,the number of the transferred embryo ,the fertilization rate and ectopic pregnancy rate among groups( P >0 .05) .The number of retrieved oocytes in group C was the lowest ,and there was significant difference between group C and other groups ( P <0 .05) .Clinical pregnancy rate of group A was lowest(25% ) and that of group D was highest (56% ) ,and there was significant difference between group A and group C ,D and E( P<0 .05) ,but there was no significant difference between group A and group B .The abortion rate of group A was highest(67% ) and that of group D was lowest(10% ) ,and there was significant difference between group A and group C ,D and E( P<0 .05) ,but there was no significant difference between group A and group B .[Conclusion] Hydrosalpinx may decrease the implantation rate of embryos and increase the abortion rate .Treatments for hydrosalpinx before IVF-ET are helpful for increasing embryo implantation rate and improving the pregnancy outcome .Proximal tubal ligation and distal tubal salpingostomy by laparos-copy can be considered for the suitable treatment of hydrosalpinx .
2014, Vol. 31 
