Abstract：[Objective] To evaluate the value of thinprep cytologic test (TCT ) ,electronic colposcopy and colposcopically directed biopsy pathology in the diagnosis of high - level cervical intraepithelial neoplasia (CIN) .[Methods]A total of 247 patients with high squamous intraepithelial neoplasia(HSIL) diagnosed by TCT in our hospital from Jan .2009 to May 2013 received electronic colposcopy ,and were diagnosed by ima-ges .Cervical biopsies were performed for pathological examination .The results of TCT were compared with the results from electronic coloposcopy and colposcopically directed biopsy pathology .The pathology of 156 cases by colposcopy was compared with the pathology by paraffin section .[Results]Among 247 cases of HSIL by TCT ,221 cases(89 .5% ) were high -level CIN (CINⅡ and CINⅢ ) diagnosed by colposcopically directed biopsy pathology ,and 5 cases(2 .0% ) were infiltrating carcinoma .The sensitivity and positive predictive value of electronic colposcopy for the diagnosis of cervical disease were 98 .7% (231/234) and 95 .9% (231/241) ,re-spectively .There was no significant difference between colposcopy inspection and colposcopically directed bi-opsy pathology( P>0 .05) .There was significant difference between colposcopically directed biopsy pathology and postoperative paraffin section pathology ( P<0 .05) .[Conclusion] TCT is an effective method for screen-ing high-level CIN .Electronic colposcope is an important and reliable clinical examination method for the auxiliary diagnosis of high -level CIN .Typical abnormal cervical images under colposcopy have a critical diag-nostic value in high -level CIN and cervical cancer .Single colposcopically directed biopsy pathology can not take place of postoperative pathological diagnosis .
引用本文:
厉碧荣%李劼%魏颖颖. TCT,电子阴道镜在高级别宫颈上皮内瘤变的诊断作用[J]. 医学临床研究, 2014, 31(3): 524-526.
LI Bi-rong%LI Jie%WEI Ying-ying. Role of TCT and Electronic Colposcopy in the Diagnosis of High -level Cervical Intraepithelial Neoplasia. 医学临床研究, 2014, 31(3): 524-526.
2014, Vol. 31 
