Abstract：[Objective]To investigate and analyze the prevalence of hyperhomocysteinemia ,hyperferriti-naemia and hyperuricemia in middle-aged male patients with hyperlipidemia .[Methods]Male patients(aged 40~60 years old) with hyperlipoidemia and subjects with normal blood lipid and the same age in our hospital were chosen .All patients had no nephrosis and recently had not taken drugs affecting the metabolism of homo-cysteine(Hcy) ,ferritin(Ferr) and uric acid(UA) .The levels of Hcy ,Ferr and UA were determined .[Re-sults] The levels of Hcy(15 .83 ± 5 .79μmol/L) ,Ferr(330 ± 74ng/ml) and UA(380 ± 90μmol/L) in hyperlipi-demia group were higher than those in normal group(8 .58 ± 4 .26μmol/L ,241 ± 87ng/ml and 325 ± 86μmol/L , respectively) ,and there was significant difference( P < 0 .01) .The morbidity of hyperhomocysteinemia(21 . 3% ) ,hyperferritinaemia(21 .6% ) and hyperuricemia(36 .5% ) in hyperlipidemia group were higher than those in normal group(10 .2% ,8 .1% and 16 .8% ,respectively) ,and there was significant difference( P <0 .01) . Different age groups were compared .Hcy level in 50~60 age group was higher than that in 40~49 age group ( P <0 .01) ,but there was no significant difference in the morbidity of hyperhomocysteinemia between these two age groups( P>0 .05) .There was no significant difference in the levels of Ferr and UA and the morbidity of hyperferritinaemia and hyperuricemia between these two age groups ( P > 0 .05) .[Conclusion] Compared with normal blood lipid group ,the morbidity of hyperhomocysteinemia ,hyperferritinaemia and hyperuricemia in middle-aged male patients with hyperlipidemia is higher ,and the levels of Hcy ,Ferr and UA are also high-er .It is important to monitor the levels of Hcy ,Ferr and UA in these special people for clinical practice .
基金资助:秦皇岛市科技研究与发展指导计划项目(项目编号201101A289)
引用本文:
李宗锋%李洪臣. 中年男性高脂血症患者伴发高同型半胱氨酸和高铁蛋白及高尿酸血症情况调查及分析[J]. 医学临床研究, 2014, 31(3): 420-422.
LI Zong-feng%LI Hong-chen. Survey on the Prevalence of Hyperhomocysteinemia,Hyperferritinaemia and Hyperuricemia in Middle-age Male Patients with Hyperlipidemia. 医学临床研究, 2014, 31(3): 420-422.
2014, Vol. 31 
