Abstract:【Objective】To investigate the significance of the capillary centrifugation method in identification of RhCcEe blood group in patients with chronic aplastic anemia (CAA) after blood transfusion.【Methods】 A total of 103 post-transfusion CAA patients were tested for RhCcEe blood group using three methods: microcolumn gel card method, capillary centrifugation method, and improved capillary centrifugation method. The results were compared with those of the polymerase chain reaction-sequence specific primer (PCR-SSP) method.【Results】 In RhCcEe blood group detection, the detection rate of the improved capillary centrifugation method was 71.84% (74/103), which was higher than that of the capillary centrifugation method (46.60%, 48/103) and the microcolumn gel card method (18.45%, 19/103), with statistically significant differences (P<0.05). The detection rate of the capillary centrifugation method was higher than that of the microcolumn gel card method (P<0.05). Among CAA patients, the detection rate of RhCcEe blood group by the improved capillary centrifugation method was 25.00% in those with transfusion interval <14 days, which was lower than those with transfusion interval of 14-28 days (75.29%) and interval >28 days (80.00%) (P<0.05). No significant difference was found between patients with intervals of 14-28 days and those with >28 days (P>0.05).【Conclusion】In RhCcEe blood group identification of CAA patients, the improved capillary centrifugation method shows a relatively higher detection rate. Moreover, the detection rate increases with the extension of the transfusion interval, making it suitable for rapid auxiliary diagnosis of RhCcEe blood group in clinical practice.
陈晓红, 李丹, 卢丽君. 毛细管离心法在慢性再生障碍性贫血输血后患者RhCcEe血型鉴定中的应用价值[J]. 医学临床研究, 2025, 42(10): 1760-1762.
CHEN Xiaohong, LI Dan, LU Lijun. Significance of Capillary Centrifugation Method in Identification of RhCcEe Blood Group in Patients with Chronic Aplastic Anemia after Transfusion. JOURNAL OF CLINICAL RESEARCH, 2025, 42(10): 1760-1762.
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